Research Keywords:
- Chemical Biology
- Drug Design
- Targeted Degradation Therapies
- RNA-Targeted Therapy
- Antisense Oligonucleotides (ASOs)
- Small Molecules
Research Highlights:
The Benhamou Laboratory operates at the interface of chemistry and biology, where organic chemistry and molecular biology converge to design innovative therapeutic solutions. The team combines expertise in synthetic chemistry—creating small molecules, oligonucleotides, and degraders—with advanced biological techniques to evaluate their effects at the cellular and molecular levels. This interdisciplinary approach enables the targeting of challenging biological systems and addresses unmet medical needs across various diseases.
By integrating synthetic chemistry with biological evaluation, the laboratory designs, synthesizes, and validates novel therapeutic agents, advancing both basic science and translational research. Their approach proposes novel strategies for designing drugs for cancer, metabolic disorders, infectious diseases, genetic diseases, and brain disorders.